Organic Chemistry, International 4th Adaptation

Description

By (author) Klein David R.

:

Organic Chemistry

Organic Chemistry 4th edition provides a comprehensive, yet accessible treatment of all the essential organic chemistry concepts covered in a two-semester course. The textbook includes all the concepts covered in a typical organic chemistry textbook but is unique in its skill development approach to the subject. Presented with a skills-based approach that bridges the gap between organic chemistry theory and real-world practice, the book places special emphasis on developing the problem-solving skills through applied exercises and activities. Numerous hands-on activities and real-world examples are integrated throughout the text to help students understand both the “why” and the “how” behind organic chemistry.

This international adapted edition offers new and updated content with improved presentation of all course material. The text adopts greater focus on retrosynthetic strategies for synthesis and skill-building. Some of the chapters include updates in nomenclature, structural presentation, mechanisms, kinetic data and recent developments in synthesis and applications. The book presents ample opportunity for practice and assessment with numerous practice problems, review questions, SkillBuilder activities, and up-to-date literature-based problems.

This book and series is authorized for sale in Europe, Middle East, Africa, Asia, Australia and New Zealand only and may not be exported. The content is comprehensively adapted to international requirements and materially different from similar products for other markets including the authorized U.S. counterpart of this title.

Table of contents:

1 A Review of General Chemistry: Electrons, Bonds, and Molecular Properties 1

1.1 Introduction to Organic Chemistry 2

1.2 The Structural Theory of Matter 3

1.3 Electrons, Bonds, and Lewis Structures 4

1.4 Identifying Formal Charges 7

1.5 Induction and Polar Covalent Bonds 8

1.6 Reading Bond- Line Structures 11

1.7 Atomic Orbitals 14

1.8 Valence Bond Theory 17

1.9 Molecular Orbital Theory 18

1.10 Hybridized Atomic Orbitals 20

1.11 Predicting Molecular Geometry: VSEPR Theory 26

1.12 Dipole Moments and Molecular Polarity 30

1.13 Intermolecular Forces and Physical Properties 33

WorldLinks Biomimicry and Gecko Feet 37

BioLinks Drug- Receptor Interactions 38

1.14 Solubility 39

BioLinks Propofol: The Importance of Drug Solubility 40

Review of Concepts and Vocabulary • SkillBuilder Review Practice Problems • Integrated Problems • Challenge Problems

2 Molecular Representations 49

2.1 Molecular Representations 50

2.2 Bond- Line Structures 52

2.3 Identifying Functional Groups 54

BioLinks Marine Natural Products 55

2.4 Carbon Atoms with Formal Charges 57

2.5 Identifying Lone Pairs 57

2.6 Three- Dimensional Bond- Line Structures 60

BioLinks The Opioids 61

2.7 Introduction to Resonance 62

2.8 Curved Arrows 64

2.9 Formal Charges in Resonance Structures 66

2.10 Drawing Resonance Structures via Pattern Recognition 68

2.11 Assessing the Relative Importance of Resonance Structures 73

2.12 The Resonance Hybrid 77

2.13 Delocalized and Localized Lone Pairs 79

Review of Concepts and Vocabulary • SkillBuilder Review Practice Problems • Integrated Problems • Challenge Problems

3 Acids and Bases 91

3.1 Introduction to Brønsted- Lowry Acids and Bases 92

3.2 Flow of Electron Density: Curved- Arrow Notation 92

BioLinks Antacids and Heartburn 94

3.3 Brønsted- Lowry Acidity: Quantitative Perspective 95

BioLinks Drug Distribution and pK a 101

3.4 Brønsted- Lowry Acidity: Qualitative Perspective 102

3.5 Brønsted- Lowry Aci